This Podcast Will Kill You

There is something uniquely tragic and terrifying about carbon monoxide poisoning. The way it comes on quietly, without warning. How it alters your reality and changes your behavior. The fact that without a carbon monoxide detector, we can’t smell or taste or see or otherwise sense this poisonous gas. Humans have been dealing with the threat of carbon monoxide poisoning since long before we were a species, and only recently have we developed the skills and knowledge to contend with it. In this episode, we get into the details of carbon monoxide poisoning - why it’s deadly, what symptoms look like, and how we manage cases - before delving into the history of our relationship with the gas. How many ghostly apparitions were actually instances of CO poisoning? What maritime mysteries can be explained by the presence of the gas? And where does carbon monoxide poisoning still remain very much an issue today? Tune in for all the details.
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It’s got all the ingredients for a classic TPWKY episode: Deadly zoonotic bacterium (Burkholderia mallei). Tier 1 Select Agent role in war (greatest risk from a bioterrorism perspective). Historically caused devastating outbreaks resulting in mass casualty (of equids). And yet few people know what glanders is (unless you’ve recently watched The Americans tv show). This week, we’re aiming to lift glanders out of obscurity and bring it the attention it so deserves. What exactly is Burkholderia mallei and how does it cause the painful and lingering symptoms it’s known for? When did glanders first strike, and how did it play a role in the US Civil War? Why does it currently rank high up on the list of possible agents of bioterrorism? Tune in to find out all this and more!
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Since his first appearance in A Study in Scarlet in 1887, Sherlock Holmes has captured hearts and imaginations around the world. Featured in countless tv shows, movies, books, plays, comic books, songs, and other media, Holmes has been firmly cemented as one of the most recognizable characters globally. But less well known is the man whose observational prowess inspired Arthur Conan Doyle to create his famous detective in the first place: Scottish surgeon Dr. Joseph Bell. In Sleuth-Hound: The Case of the Real Sherlock Holmes, New York Times bestselling author and historian of medicine Dr. Lindsey Fitzharris brings long overdue recognition to the man behind the icon. Through her captivating storytelling, Fitzharris transports readers to 19th century Edinburgh, a revolutionary time for medicine and forensic science, and reveals how Dr. Joe Bell was at the center of it all. As pathologist at the Royal Infirmary, he impressed medical students by using his preternatural skills of observation to make a diagnosis, and as a frequent consultant of the Edinburgh police force, he applied those same skills to solve crimes. Tune in for a behind-the-Holmes peek into the man and world that gave rise to this famous detective.
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Looking to get swole (do people still say that)? Want to rewind the clock and smooth those bothersome wrinkles? Trying to lose weight rapidly and without a prescription? If you’ve spent any time on social media lately, chances are you’ve been inundated with ads, influencers, and podcast bros extolling the seemingly unlimited powers of peptides. With GLP-1s turning ‘peptide’ into a household word, the online “wellness” market has been flooded with the newest iteration of snake oil salesmen. According to them, these bespoke peptide combinations can reverse baldness, build muscle, and restore youth, all for the low, low price of… you get the idea. But what the heck even are peptides? How are they regulated? Is there any evidence to support these bold claims? What isn’t your peptide dealer telling you? Tune in to find out.
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Come one, come all to learn of the miraculous news we’re buzzing to share with you at this limited time, low price offer. If you’ve been troubled by aches and pains, sores and sneezes, look no further than this very special episode - good for whatever ails you. Brimming with historical detail and outlandish claims, we’re marching through the wild west of patent medicines in the 19th century. We begin with the widespread rejection of professional medicine in the 1820s (sound familiar??) and continue through the century as quack doctors and snake oil salesmen proliferate and hawk their fraudulent goods across the landscape. Fueled by a lack of regulation and the eternal desire for a cure-all, these fraudsters grew ever wealthier and more daring in the claims they made. When consumer protections finally kicked in at the turn of the 20th century, it left people wondering: did the snake oil salesman truly die or did he just take on a new disguise? Tune in to learn that the more things change, the more they stay the same.
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