This episode is brought to you by Paleovalley and Athletic Greens.Food should be a tool for helping us feel our best. But most people don’t realize what kind of impact many of the foods they eat are having on their blood sugar—and subsequently their entire body. The symptoms of blood sugar imbalances are everyday occurrences for most people. Feeling hungry even when you just ate, craving sweets, and dealing with acne, hormonal imbalances, and signs of aging, like wrinkles, are just a few of the many symptoms of blood sugar swings. When these continue to go unchecked, more severe dysfunctions can occur, like type 2 diabetes, infertility, fatty liver disease, and dementia. In today’s episode, I talk with Dr. Ben Bikman, Dhru Purohit, and Dr. Ronesh Sinha about how common dietary patterns like eating simple carbs throughout the day create constant insulin spikes leading to insulin resistance, which in turn contributes to many diseases and aging. Dr. Ben Bikman is a renowned metabolic research scientist and a popular speaker on human metabolism and nutrition. Backed by years of research, Dr. Bikman’s mission is to help the world appreciate the prevalence and relevance of insulin resistance. He is the author of the book Why We Get Sick, which offers a thought-provoking yet real solution to insulin resistance and reversing prediabetes, improving brain function, shedding fat, and preventing diabetes. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset.Dr. Ronesh Sinha, author of The South Asian Health Solution, is an internal medicine physician who runs a lifestyle clinic in Silicon Valley focused on reversing insulin resistance in ethnically diverse patients. He is also an expert in corporate wellness and serves as the Chief Medical Officer for the Silicon Valley Employer Forum, where he serves as a global advisor to shape health benefits for over 55 major Silicon Valley companies. This episode is brought to you by Paleovalley and Athletic Greens.Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal.AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman.Full-length episodes of these interviews can be found here:Dr. Ben BikmanDhru PurohitDr. Ronesh Sinha Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker.Many people think of metabolism as one specific system in the body, when in fact it’s the sum of many different processes that are serving other vital roles for us as well. Our bodies are not closed systems, so our environment, social networks, diet, hormones, microbiome, genetics, and more, all influence how well our metabolism works, or how well we can extract energy from our food. I’m so happy to sit down with my good friend Dr. William Li to talk about what metabolism really means, why the old way of thinking about metabolism hasn’t helped us, and how to make positive impacts on our metabolism at any age. Dr. William Li is a world-renowned physician, scientist, speaker, and author of Eat to Beat Disease - The New Science of How Your Body Can Heal Itself. He is best known for leading the Angiogenesis Foundation. His groundbreaking work has impacted more than 70 diseases, including cancer, diabetes, blindness, heart disease, and obesity. An author of over 100 scientific publications in leading journals such as Science, the New England Journal of Medicine, The Lancet, and more, Dr. Li has served on the faculties of Harvard, Tufts, and Dartmouth Medical School.This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker.You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.Right now, get 40% off your Cozy Earth sheets at cozyearth.com and use code MARK40.InsideTracker is offering my community 20% off at insidetracker.com/drhyman.Here are more details from our interview (audio version / Apple Subscriber version):Shifting away from the idea that eating less and exercising more is the key to weight loss (4:51 / 2:12) How calories affect metabolism (13:14 / 11:25)  Research measuring the four phases of metabolism as we age (16:07 / 13:36) What is metabolism? (24:03 / 21:26) Common myths about metabolism (28:35 / 24:37) Supporting the gut microbiome to raise metabolism and promote health (36:18 / 32:03) Foods that mimic caloric restriction (40:27 / 36:10) Our body’s ability to reverse disease (52:59 / 46:21) Reducing stress in a doomscrolling society (54:07 / 49:30) How to restore health to your metabolism (56:03/ 51:56) Mentioned in this episodePerspective: Obesity—an unexplained epidemicCompeting paradigms of obesity pathogenesis: energy balance versus carbohydrate-insulin modelsDaily energy expenditure through the human life courseGet a copy of Dr. Li’s book, Eat to Beat Disease: The New Science of How Your Body Can Heal Itself, here and check out his Masterclass with Dr. William Li here. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

This episode is brought to you by Rupa Health, Thrive Market, and Comvita.Today, as part of my Masterclass series, I’m answering personal questions my team put together from the “Let’s Get Closer” card deck. I am joined by my good friend and podcast host, Dhru Purohit, to give you a peek into my personal life as I answer questions about my greatest struggles, what I’m addicted to, the best advice I’ve received, and much more. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset.This episode is brought to you by Rupa Health, Thrive Market, and Comvita. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Thrive Market is an online membership-based grocery store that makes eating well convenient and more affordable. Join today at thrivemarket.com/hyman to receive an extra $80 worth of free groceries with your first order. Comvita offers the most premium, pure, well-researched, and sustainably sourced Manuka products available on the market today. You can learn more at comvita.com, and enter code Hyman25 for 25% off all Manuka honey and bee products. (This offer does not apply to bundles or sale items.) In this episode, we discuss (audio version / Apple Subscriber version):The last time I asked for help (5:20 / 2:12)A time when I felt the most alive (7:04 / 4:45) The way I like to be comforted when I’m sad or upset (12:00 / 9:38) What I am addicted to (14:08 / 11:47) What I miss about being a kid (21:42 / 18:03)Characteristics I most admire in others (25:06 / 21:26) The greatest struggles I’ve overcome (25:50 / 22:10) The best advice I’ve received (27:57 / 24:18) My biggest fear (30:34 / 26:54)My definition of success (33:14 / 29:37) The most miraculous thing I’ve experienced (34:55 / 31:17)Something I can’t explain (40:55 / 37:15) How I’d like to be remembered (46:28 / 42:50) Mentioned in this episode:Let’s Get Closer by Intelligent ChangeInner.UHow to Conquer Your Mind to Live Your Best Life with Colin O’BradyThe Spontaneous Fulfillment of Desire by Deepak Chopra Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

This episode is brought to you by ButcherBox and Athletic Greens. Our gut is a powerful control center, due to its bidirectional communication with the brain, which we call the gut-brain axis. This links the emotional and cognitive centers of the brain with intestinal function. Certain conditions, such as irritable bowel syndrome (IBS), are tied to imbalances in the gut-brain axis and can benefit from taking a systems approach in healing, which includes looking at diet, the microbiome, stress management, and more. In today’s episode, I talk with Dr. Todd LePine, Dr. Emeran Mayer, and Dr. George Papanicolaou about various root causes of irritable bowel syndrome, including microbiome imbalance, parasites, and stress. Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine certified practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. Dr. Emeran Mayer is the author of The Gut-Immune Connection as well as The Mind-Gut Connection. He has studied brain-body interactions for the last 40 years, is the executive director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience, and is the founding director of the UCLA Brain Gut Microbiome Center at the University of California at Los Angeles. His research has been supported by the National Institutes of Health for the past 25 years, and he is considered a pioneer and world leader in the area of brain-gut microbiome interactions and its clinical implications.⁣ Dr. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is board certified in Family Medicine from Abington Memorial Hospital. He is also an Institute for Functional Medicine practitioner. He worked on the Navajo reservation for four years at the Chinle Comprehensive Medical Facility, where he served as the Outpatient Department Coordinator. In 2000, he founded Cornerstone Family Practice in Rowley, MA. In 2015, he established Cornerstone Personal Health, a practice dedicated entirely to Functional Medicine. Dr. Papanicolaou joined The UltraWellness Center in 2017. This episode is brought to you by ButcherBox and Athletic Greens. If you sign up today, ButcherBox will give you two ribeye steaks for free in your first box. Just go to butcherbox.com/farmacy to claim this deal. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Full-length episodes of these interviews can be found here:Dr. Todd LePineDr. Emeran MayerDr. George Papanicolaou Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

This episode is brought to you by Mitopure, InsideTracker, and Rupa Health.The topic of veganism is hotly debated in terms of health and environmental stewardship. But how did the idea that being vegan is the best way to eat for our bodies and the planet develop in the first place? The answer is more complex than you might think. On this episode of The Doctor’s Farmacy, Jayne Buxton challenges the notion that veganism is the cure for disease and climate change and explains how we got here. A British-Canadian, Jayne Buxton is an author of both fiction and non-fiction. She spent fifteen years doing research-intensive work as a management consultant for a major firm before writing her 1998 book, Ending the Mother War: Starting the Workplace Revolution, which explored the entrenched positions and false choices faced by women wanting to combine motherhood with careers. Jayne subsequently spent years working in the field of work-life balance, advising both parents and corporations, before turning to writing full time. Her new book, The Great Plant-Based Con, challenges the dominant narrative about the vegan diet and proposes a compelling new perspective.This episode is brought to you by Mitopure, InsideTracker, and Rupa Health.Get 10% off Mitopure at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout.Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman.Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.Here are more details from our interview (audio version / Apple Subscriber version):The origins of the overarching mythology that veganism is best for human, animal, and planetary health (5:04 / 2:24) How Big Food, Big Agriculture, and Big Pharma benefit from widespread veganism (7:17 / 4:50) Why the movie The Game Changers was a tipping point for Jayne to write her book (10:58 / 8:13) Countries that have banned vegan diets for children (14:55 / 12:07) My experience treating vegan patients (19:01 / 16:07) Frequent health issues that occur from vegan diets (22:50 / 18:08) Navigating the science, and subsequent dietary recommendations, around vegan diets and eating meat (29:54 / 25:27) Building soil health through regenerative agriculture (51:05 / 45:35)Pervasive myths around cows and methane production (55:05 / 50:40) Jayne’s recommendations for how to eat for optimal human, animal, and planetary health (1:03:53 / 59:38)Learn more about Jayne Buxton and her work at thegreatplantbasedcon.com and get her book, The Great Plant-Based Con: Why eating a plants-only diet won't improve your health or save the planet, here. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.