Biohacking Beauty: The Anti-Aging Skincare Podcast

Most skincare routines are built by accumulation: a serum that went viral, a cream a friend swore by, whatever promised firmer skin that month. But what drives skin aging at 25 is not what drives it at 45, so a routine that never changes its priorities can spend years working on the wrong problem.
And your birthday is only part of the picture. Some people's skin is running a decade ahead of their age, perimenopause can change what skin needs years before the 40s arrive, and the routine you will actually stick with is usually shorter than the one you think you need. So before you add another product, it is worth knowing what changes in your skin from one decade to the next and what each stage should prioritize.
In this Biohacking Beauty Class, we walk through a skincare protocol for every decade, from protection in your 20s to correction in your 30s and recovery in your 40s, 50s, and beyond. We get into the research tying sun exposure to 80% of visible facial aging, why NAD+ declines in aging skin, what makes many exosome formulas questionable, how to tell if your skin is aging ahead of your age, and the red light specs that actually matter.
What’s Discussed:
(02:17) Why your skin's age matters more than the number on your birthday.
(03:09) The "attention budget" and why a shorter routine often gets better results.
(04:44) The research linking sun exposure to 80% of visible facial aging.
(06:20) What happened when adults used sunscreen every day for four and a half years.
(12:06) Why NAD+ declines in aging skin and what changes after 30.
(15:03) How spermidine and autophagy help skin clear out what has expired.
(22:08) Why exosomes cannot survive alongside vitamin C, acids, and peptides in the same formula.
(24:04) The part of aging in your 40s that sunscreen cannot fully cover.
(26:10) Why perimenopause and menopause mean moving up a stage, whatever your age.
(31:22) A first look at the Youth Activating Ampoule and why some actives have to stay freeze-dried.
(42:05) What to use at home in the weeks around microneedling and laser treatments.
(45:25) What the research says about red light therapy and the specs worth paying for.
(51:53) How to find out if your skin is aging ahead of your age.
Listen to this episode of Biohacking Beauty before you add another product to your routine, so you know what your skin needs at the stage it is actually in.
Resources Mentioned:
Skincare by Age protocol: https://www.younggoose.com/pages/science
Decade-by-Decade Skincare Field Guide
Young Goose AI Facial Scanner
SkinOS™ Longevity Test
Find a Young Goose Professional
Previous Episodes Mentioned:
Anastasia and Amitay with Dave Asprey on The Human Upgrade
Find more from Young Goose:
Website: Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare

There is an interesting contradiction in the way we talk about aging. We celebrate using technology to improve sleep, metabolism, cognition, recovery, and longevity, but when the same mindset is applied to appearance, the conversation can suddenly become much more judgmental.
In this episode of Biohacking Beauty, we sit down with Dave Asprey to explore that tension. We get into why he chose a facelift after major weight loss, whether cosmetic procedures belong in the biohacking conversation, and why wanting to look younger is often treated differently from wanting the rest of your body to function younger.
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, CEO of Upgrade Labs, host of The Human Upgrade, and co-founder of Unlimited Life. We also talk about how he prepares his body before procedures, what he thinks people misunderstand about peptides, and his takes on GLP face, collagen supplements, Botox, stem cells, and the other tools people are using to change how they age.
What’s Discussed:
[13:02] Why Dave ultimately chose a facelift after major weight loss.
[15:24] Where non-surgical skin treatments reached their limit for the amount of excess skin he wanted to address.
[18:58] Why copying someone else’s longevity or supplement stack can backfire.
[28:59] Where to start when your biological-age markers look good but you still do not like what you see in the mirror.
[30:07] Why sleep, recovery, HRV, and other foundational markers still matter when thinking about aging.
[37:52] The stigma around cosmetic procedures in biohacking and why Dave questions where that line is drawn.
[44:56] Why he believes fear around aging and medical procedures can affect the body’s stress response.
[54:25] GLP-1s, muscle loss, and the changes people notice in facial appearance after weight loss.
Listen to this episode of Biohacking Beauty for a conversation about where “aging naturally” ends, where biohacking begins, and why that line becomes much more complicated when appearance enters the picture.

Find more from Young Goose:
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off atyounggoose.com
Instagram: @young_goose_skincare

Find more from Dave Asprey:
Website:daveasprey.com
LinkedIn: Asprey
Instagram:@dave.asprey
Facebook: Daveaspreyofficial
YouTube: DaveAspreyBPR
TikTok: @daveaspreyofficial
Book: “Heavily Meditated”: https://daveasprey.com/heavily-meditated/

Peptides are everywhere in skincare right now. They are in serums, moisturizers, lip products, cleansers, body washes, and even shampoos, all promising some version of smoother skin, more collagen, or fewer visible signs of aging.
But seeing “peptides” on a label tells you very little about whether the product can actually deliver those results. Which peptide is being used? Is there research behind that specific ingredient? Is there enough of it in the formula? Can it get through the skin barrier? And what happens when it is combined with everything else inside the bottle? So before you buy another peptide serum because the ingredient sounds impressive, it is worth knowing what actually makes a peptide useful for your skin and how formulation, delivery, concentration, and the rest of your routine can affect whether it works at all.
In this Biohacking Beauty Class, we are separating the science from the marketing around topical peptides. We get into which ones have more evidence behind them, what “Botox in a bottle” gets wrong, why some peptide products make more sense than others, and what to look for if your goal is supporting collagen, softening fine lines, and keeping your skin functioning well as it ages.
What’s Discussed:
(01:47) Do peptides actually belong in everything from serums to body wash?
(05:17) The biggest red flag when a skincare product uses peptides as the main selling point.
(08:26) What should actually back up an anti-aging peptide claim.
(11:11) Which topical peptides have more evidence behind them.
(13:01) Why neuropeptides are not really “Botox in a bottle.”
(15:54) What to know about using peptide products with vitamin C, retinoids, and other actives.
(17:46) Why pH, concentration, and the other ingredients in a formula can affect peptide stability.
(21:14) What actually makes a topical peptide product more likely to work.
(22:45) Why healthy skin function still matters when you are trying to support collagen and repair.
(25:09) If you could only add one peptide product to your routine, which type should it be?
Listen to this episode of Biohacking Beauty before another peptide claim on a skincare label convinces you to spend more without knowing what is actually inside the formula.
Previous Episodes Mentioned:
Nathalie Niddam: Peptides, Bioregulators, and the Truth About Skin Longevity
https://podcasts.apple.com/us/podcast/nathalie-niddam-peptides-bioregulators-and-the/id1552026927?i=1000736397042
Nathalie Niddam: The Potential of Peptides in Skin Health and Anti-Aging
https://podcasts.apple.com/au/podcast/nathalie-niddam-the-potential-of-peptides-in-skin/id1552026927?i=1000642759851
Peptides episodes to watch:
Peptides, Bioregulators & The Truth About Skin Longevity | Nathalie Niddam:
: https://www.youtube.com/watch?v=2AoqcXJ_MMc
Why Peptides Are Not the Shortcut Biohackers Think They Are with Chris Duffin: https://www.youtube.com/watch?v=UNPhDZXY6kw
Peptides, Hormones, and the Anti-Aging Protocol Most Women Start Too Late: https://www.youtube.com/watch?v=b_CTcFjeyqQ&t=428s
GHK-Cu Explained: The Copper Peptide That Signals Collagen Repair: https://www.youtube.com/watch?v=qGDNyVtZjl4
Find more from Young Goose:
Website: Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare

You probably know which side of your face you prefer in photos. One jawline may look sharper. One cheek may sit differently. One under-eye may look darker. And while some facial asymmetry is completely normal, the way you use your mouth can also influence how the two sides of your face function over time.
In Part 2 of our conversation with Dr. Staci Whitman, we look at facial aging from inside the mouth. We get into how one-sided chewing, bite patterns, tongue function, palate width, airway health, and jaw structure can influence facial symmetry and the way changes become visible in the face. We also explore what adults can realistically do when the issue is structural rather than purely cosmetic. Dr. Staci breaks down the conversations happening around mastic gum, myofunctional therapy, palate expansion, MARPE, oral appliances, and tongue-tie releases, including why changing the way the mouth functions is much more complicated than trying the latest jawline trend online.
Dr. Staci Whitman is a board-certified pediatric dentist and Functional Medicine Certified Practitioner whose work focuses on functional dentistry, airway health, craniofacial development, the oral microbiome, and the mouth-body connection. She is the co-founder of the Institute for Functional Dentistry and founder of Bloom + Brighten.
What’s Discussed:
[1:37] Why persistent dark under-eyes may sometimes point to airway issues, inflammation, and facial structure rather than pigmentation alone.
[3:32] What happens to the jaw and the bones supporting the face as we age.
[6:44] How chewing predominantly on one side may contribute to differences between the two sides of the face.
[10:55] What your chewing patterns, saliva, and cavities may reveal about how you are using your mouth.
[17:09] Whether mastic gum and jaw exercises can actually change the appearance of an adult face.
[20:00] How tongue function, swallowing, and breathing are addressed through myofunctional therapy.
[21:50] Why a narrow palate may require more than simply changing your tongue position.
[22:30] What adults should know about palate expansion, MARPE, and oral appliances.
[31:26] Why finding a tongue tie does not automatically mean releasing it is the first step.
[40:49] Who to see when you suspect your bite, tongue, airway, or jaw function may be affecting your face.
Listen to this episode of Biohacking Beauty to learn why facial asymmetry may be giving you clues about what is happening inside your mouth.

Find more from Young Goose:
Website: www.younggoose.com/
Use code PODCAST10 to get 10% OFF your first purchase, and if you are a returning customer use code PODCAST5 to get 5% OFF.
Instagram: @young_goose_skincare

Find more from Dr. Staci Whitman:
Website: doctorstaci.com
Instagram: @doctor_staci
TikTok: @doctor_staci
YouTube: youtube.com/channel/
Book: SPIT: Why Your Mouth-and Its Microbes-Are the Secret to Whole-Body, Lifelong Health
Read Dr. Staci’s newsletter: substack.com/@doctorstaci

Resources
Find an oral-systemic health practitioner through AAOSH: aaosh.org/find-a-practitioner
Search the IAOMT directory for a biological dentist or health professional: iaomt.org/for-patients/Search/?ppage=dashboard
Find an airway-focused practitioner through AAPMD: aapmd.org/find-aapmd-professional
Search The Breathe Institute provider directory: breatheops.com/directory/the-breathe-institute
Learn more about the Institute for Functional Dentistry: functionaldentistry.org/

You can invest in your skincare, protect your collagen, and do everything you can to age well, while completely overlooking something that sits only a few inches away from your skin: your mouth. The way you breathe, chew, swallow, care for your gums, and support your oral microbiome can influence far more than your teeth.
In this episode of Biohacking Beauty, we sit down with Dr. Staci Whitman to explore how oral health connects to facial structure, airway health, under-eye darkness, inflammation, blood flow, and the appearance of your skin. We also get into the everyday oral habits that may be working against you, what actually matters in an oral routine, and the facial signs that can make Dr. Staci suspect something deeper is going on.
Dr. Staci Whitman is a board-certified pediatric dentist and Functional Medicine Certified Practitioner who specializes in the mouth-body connection, airway development, craniofacial growth, and the oral microbiome. She is the co-founder of the Institute for Functional Dentistry and founder of Bloom + Brighten, bringing functional medicine and systems biology into a part of health that is still often treated separately from the rest of the body.
What’s Discussed:
(01:17) Why humans chew dramatically less today and what that can mean for facial development.
(05:57) How mouth breathing, narrow airways, and modern eating habits can show up in the face.
(11:23) The oral bacteria involved in nitric oxide production and why blood flow matters for skin.
(13:02) Why saliva is one of the most overlooked parts of oral health and what happens when your mouth stays dry.
(16:50) Why Dr. Staci believes dentistry is missing a major piece of the longevity conversation.
(24:20) What actually matters in an oral-health routine, from meal timing and nasal breathing to flossing and microbiome testing.
(31:40) How hormones, pregnancy, perimenopause, and menopause can change oral health.
(40:52) What tongue scraping actually does and what your tongue may reveal about your health.
(46:02) What Dr. Staci notices about your face, eyes, lips, posture, and breathing before she even looks at your teeth.
Listen to this episode of Biohacking Beauty to learn why the way your face looks may be influenced by habits you have never considered part of your beauty routine.

Find more from Young Goose:
Website: www.younggoose.com/
Use code PODCAST10 to get 10% OFF your first purchase, and if you are a returning customer use code PODCAST5 to get 5% OFF.
Instagram: @young_goose_skincare

Find more from Dr. Staci Whitman:
Website: doctorstaci.com
Instagram: @doctor_staci
TikTok: @doctor_staci
YouTube: youtube.com/channel/
Book: SPIT: Why Your Mouth-and Its Microbes-Are the Secret to Whole-Body, Lifelong Health