Biohacking Beauty: The Anti-Aging Skincare Podcast

Skincare trends are moving fast, and it can be hard to tell what is actually worth your attention. One day everyone is talking about red light masks, then peptide lip balms, at-home microneedling, men’s skincare, acne protocols, or another product claiming to be the next thing your skin needs.
The problem is that some of these tools can be useful, but the way they are marketed often leaves out the context that matters most. A red light device is not just about wavelength. Acne is not just about bacteria. Peptides in skincare are not automatically effective just because the word is on the label. And not every trend deserves to become the center of your routine.
In this Q&A episode of Biohacking Beauty, we’re answering the skincare questions you sent in and breaking down what to look at before buying into the hype. We get into acne, red light therapy masks, at-home microneedling, men’s skincare, and the peptide skincare problem so you can think about these trends with more science and less noise.
What’s Discussed:
(03:14) Why acne is not just a bacteria problem.
(07:24) What to know before buying a red light therapy mask.
(13:36) The red light devices we actually use at home.
(16:06) At-home microneedling, skin barrier risk, and where to draw the line.
(21:02) Why men’s skincare is mostly marketing.
(25:10) What performance skincare may actually mean.
(29:41) Why peptide skincare claims are harder to verify than they seem.
Listen to this episode of Biohacking Beauty to understand which skincare trends deserve a closer look, what questions to ask before buying, and where the science matters more than the marketing.
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare

Peptides are being treated like the missing piece in recovery, skin longevity, fat loss, performance, and aging. The usual belief is that if you find the right compound, the right dose, or the right stack, the body will finally respond the way you want it to. But what if the protocol is not the first thing that needs to be fixed?
In this episode of Biohacking Beauty, I sit down with Chris Duffin to unpack what most peptide conversations skip: the state of the body receiving the signal. They get into why cellular terrain matters, what happens when people chase regenerative tools before the foundation is ready, and how skin can reveal whether the body is actually prepared to adapt, repair, and age well.
Chris Duffin is the Human Performance Expert, an internationally recognized authority in human performance science, and the first person in history to squat and deadlift over 1,000 pounds for multiple reps. His work sits at the intersection of strength, resilience, peptide science, executive performance, and regenerative health, which makes this conversation a rare look at what it actually takes to build a body that can respond to advanced tools instead of just relying on them.
What’s Discussed:
(02:15) Why peptides are powerful, but not the whole answer.
(05:12) What cellular terrain has to do with regeneration.
(09:18) Why looking healthy does not always mean the body is resilient.
(15:07) How peptides fit into a bigger recovery and longevity strategy.
(27:09) What peptide reactions may reveal about the body underneath.
(50:06) Why skin rejuvenation depends on the body’s ability to respond.
(01:06:05) How peptide hype is changing the longevity conversation.
Listen to this episode of Biohacking Beauty to understand what needs to happen inside the body before peptides, procedures, or any regenerative tool can actually move the needle.
Resources Mentioned:
Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/
FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Find more from Chris Duffin:
Instagram: @mad_scientist_duffin
Website: enhancedexecutive.com/

If you have been thinking about buying a LED mask, the hardest part is knowing what actually matters. The price range is all over the place, every brand seems to have some version of “FDA cleared” on the page, and a lot of the buying advice sounds scientific enough to trust. But none of that automatically tells you whether the device is strong enough to do anything meaningful for your skin.
That is why we wanted to take a closer look at an Allure post called So You Wanna Buy a LED Mask. The guide brings up the same things people usually look at before buying one: price, number of bulbs, FDA clearance, clinical trials, and how often you have to use it. Some of those details can be useful, but they can also distract from the real questions: how much light does the device actually deliver, what wavelengths does it use, and is the coverage strong enough to create meaningful stimulation?
That matters if you are about to spend a few hundred dollars on a device and you are using the wrong signals to decide. A high price, FDA clearance, or a small clinical study can make a mask sound more credible, but those details do not always answer the question you actually care about: Will this device give my skin enough stimulation to be worth using?
What’s Discussed:
(04:22) Why we are reacting to Allure’s LED mask buying guide.
(05:12) Why the $100 to $1000 LED mask price range is not very helpful.
(07:31) Why diode count matters, but output matters more.
(08:33) Whether you actually need to use a LED mask every day.
(10:55) What FDA clearance does and does not tell you.
(13:35) Why a five-subject clinical trial is not strong proof.
(15:45) The wavelengths that matter for red light therapy.
Listen to this episode of Biohacking Beauty to understand what actually matters before buying a LED mask, and why the most scientific-sounding claims are not always the ones that tell you if a device will work.
Resources Mentioned:
Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/
FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare

We have been getting the same question in our DMs for months now. Peptides are everywhere. Everyone is talking about them. But what actually has evidence behind it, what is hype, and where do hormones fit into all of this? So we went and found someone who has been living this conversation for 35 years, not just talking about it.
Dr. Jennifer Berman is a urologist, New York Times bestselling author, and one of the leading voices in female sexual and menopausal health. She pioneered the field at UCLA, runs the Berman Women's Wellness Center in Beverly Hills, and has been her own first patient through every transition she now treats. She is the kind of doctor who was doing things a decade before they became mainstream and has the clinical receipts to back all of it up.
In this episode we get into why peptides are the missing piece of the menopause puzzle, what hormones are really doing to your skin from the inside out, and how treatments that were written off as fringe became the new gold standard for longevity.
What's Discussed:
(01:42) Why peptide production declines with age and what that actually means for how women look and feel in perimenopause.
(04:04) The regulatory reality around peptides right now and why medical grade from a 503B pharmacy is the only route worth taking.
(06:07) The specific peptides with the strongest evidence for skin, muscle, fat loss, recovery, and cognitive function.
(13:12) Why your mid to late 30s is already perimenopausal by definition and why that changes when you start.
(15:02) C-Link, C-Max, and PE22-28 for mood, neuroplasticity, and cognitive protection and why Dr. Berman stacks them together.
(39:17) The exact point where topical skincare stops being enough and what hormone imbalance is doing to skin that no cream can fix.
(53:08) Why cycling your peptides matters, what receptor attenuation actually is, and why the protocol on your feed is not a clinical protocol.
By the end of this episode you will know which peptides have actual evidence behind them, where topical skincare stops working without hormonal support, and what an inside-out longevity protocol looks like from a doctor who has lived every transition she treats.
Resources Mentioned:
Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/
FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Find more from Dr. Jennifer Berman:
Website: bermansexualhealth.com/
Instagram: @jenbermanmd

Creatine has been boxed in as a gym-bro supplement for decades, but the latest research shows it's doing far more than building muscle. It buffers brain energy under sleep deprivation, supporting bone density and mood stability through perimenopause, and freeing up methyl groups for detoxification and DNA repair.
We dive deeper into this in the Biohacking Beauty Podcast with Dr. Dan Pardi. We also chat about why the bloating myth is backwards, how creatine and NAD work synergistically to support mitochondrial energy, and what topical creatine could mean for the future of skincare.
Dr. Dan Pardi is a researcher whose first study in the 1990s focused on creatine, and he has spent three decades following the science as it expanded from sports performance into brain health, healthspan, and women's physiology. He is the Chief Health Officer at Qualia Life Sciences, where the team has earned recognition from the Nutrition Business Journal for science and innovation.
His work focuses on translating peer-reviewed research into formulations that support cellular energy, methylation, and longevity.
Let's dive in.
Use code YOUNGGOOSE at https://www.qualialife.com/ for a special discount.

What's Discussed:
(4:32) Why creatine went from a niche Olympic edge to a billion-dollar category after the 1992 Games.
(11:18) The sloping-surface analogy that explains why 5 grams saturates muscle but barely touches the brain.
(15:47) How creatine buffers cognitive performance under sleep deprivation, with no decrement at baseline.
(22:05) Why the bloating myth is backwards and what intracellular hydration actually feels like.
(28:40) Topical creatine, the dermal layer, and why molecule size matters for skin delivery.
(36:22) The decade of creatine in women: bone density, mood, and energy fluctuations through menopause.
(42:15) Where the hair loss rumor really came from, and why creatine took the blame.
(51:08) Why 40% to 70% of your body's methylation goes to making creatine, and what that means for NAD stacking.

Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare

Find more from Dr. Dan Pardi:
Instagram: @drdanpardi
Substack: @drdanpardi

Find more from Qualia:
Website: qualialife.com
Instagram: @qualialife
Qualia Creatine: qualialife.com/shop/qualia-creatine