Biohacking Beauty: The Anti-Aging Skincare Podcast

Being told your labs are “normal” and your cycle is still regular does not mean your metabolism and hormones are stable. Early insulin resistance can quietly increase inflammation, drive midsection fat gain, and accelerate skin aging years before menopause is officially diagnosed.
In this Biohacking Beauty episode with Dr. Jila Senemar, we break down why regular periods do not rule out perimenopause, why building muscle is one of the most powerful metabolic tools in midlife, and how early testing like DEXA scans can reveal hidden bone loss long before standard guidelines would ever check.
Dr. Jila Senemar is a board-certified OB/GYN with more than 20 years of clinical experience. She is a menopause specialist certified by The Menopause Society and a longevity physician. Her clinical work focuses on perimenopause, menopause, hormone therapy, and midlife women’s health.
What's Discussed:
(02:57) Insulin resistance as an early midlife driver of inflammation and weight gain
(03:35) Why more cardio and restriction can worsen midlife metabolic dysfunction
(07:27) Regular periods and no hot flashes still align with early perimenopause
(09:44) Night waking and unrefreshing sleep as overlooked perimenopause symptoms
(15:01) Strength training as a metabolic and hormonal support tool in midlife
(24:40) Using DEXA scans at 40 to detect early bone density loss
(26:15) Hormone therapy framed around longevity, not just symptom relief
(41:14) Progesterone’s role in sleep, mood stability, and early perimenopause support

Find more from Young Goose:
The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change
The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter
VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com
Instagram: @young_goose_skincare

Find more from Dr. Jila Senemar MD, FACOG, MSCP:
Website: https://www.jilamd.com
Instagram: @drjilasenemar

Advanced skincare routines are more popular than ever, yet dryness, laxity, and visible aging still persist. The issue isn’t effort or discipline. It’s that skin aging is being treated as a surface-level problem instead of a cellular and structural one.
We dive deeper into this in the latest Biohacking Beauty Podcast with Jess Kane. We also chat about how cell membrane health shapes visible aging, why omega fats are widely misunderstood, and how most “liposomal” supplements never reach the cell.
Jessica Kane is the Co-Owner and Chief Marketing Officer of BodyBio, a third-generation wellness company specializing in cellular health. She works alongside healthcare practitioners and researchers to translate complex cell membrane and lipid science into practical, evidence-based solutions.
What's Discussed:
(06:17) Why advanced skincare and red light therapy still fail without cellular building blocks
(07:37) How low-fat nutrition and missing lipids weaken skin structure over time
(09:55) Cell membranes explained as the foundation of skin barrier, tone, and elasticity
(10:46) How phospholipids act as the “cement” between skin cells and prevent laxity
(13:15) Why the omega-6 to omega-3 ratio matters more than taking fish oil alone
(15:57) Why most phosphatidylcholine on the market is not truly liposomal
(18:28) How “liposomal” labeling works and why most supplements fail cellular delivery
(36:01) Why vitamin C and glutathione don’t impact collagen without proper absorption

Find more from Young Goose:
Find our Elastin Protocol here: https://younggoose.com/pages/elastin-action-protocol-landing
Find our Winter Protocol here: https://younggoose.com/pages/winter-protocol
VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery: https://younggoose.com/products/vampire-exosomes
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com/?utm_source=podcast&utm_medium=apple
Instagram: http://instagram.com/young_goose_skincare

Find more from Jess Kane:
Website: https://bodybio.com/
Instagram: https://instagram.com/jesskane
Instagram: https://www.instagram.com/bodybio/
Tiktok: https://tiktok.com/@jesskaneb

It’s Valentine’s Day, and while we don’t usually shape our work around holidays, this one felt different because we’re not just co-founders of Young Goose, we’re life partners. For us, care has always shown up in daily choices and consistency, the same philosophy behind how we think about skin longevity.
In this special episode, we flip the format and recommend ingredients to each other based on real-time skin needs. We get into methylene blue, NAD support, ectoin, retinol, and repair-focused actives through the lens of cellular energy, inflammation control, repair, and long-term resilience.
If you’re listening on Valentine’s Day, we’re honored you’re spending it with us. And if you’re tuning in any other day, we’re just as glad you’re here. Either way, this conversation is about care that lasts and the small, intentional choices that add up over time.
What's Discussed:
(03:38) Why this Valentine’s episode feels different as co-founders and life partners
(06:11) Recommending ingredients based on real-time skin needs, not bias
(12:38) Methylene blue, red light synergy, and mitochondrial skin energy
(17:04) NAD support as the currency behind repair and long-term resilience
(20:49) Ectoin, deep hydration, and protection from blue light and pollution
(25:10) Retinol results, limitations, and why peptide alternatives matter
(27:36) Sun exposure, oxidative stress, and the missing piece of post-UV DNA repair

Find more from Young Goose:
The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change
The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter
VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com
Instagram: @young_goose_skincare

Skin problems are often the body’s earliest warning sign that detoxification, inflammation control, and nutrient absorption are already compromised. When detox demand rises and recovery systems can’t keep up, skin changes and aging-related signs become more pronounced.
In this episode of the Biohacking Beauty Podcast, we sit down with Marina Moiseyeva to explore why medications and aggressive topicals increase detox load, how sweating and lymphatic movement support skin longevity, and why “Ozempic face” is driven by muscle, bone, and nutrient loss rather than fat alone.
Marina Moiseyeva is a Functional Medicine Practitioner and Board Certified Family Nurse Practitioner with 16 years of clinical experience. She is a Certified Diplomate in Anti-Aging and Regenerative Medicine, a member of the American Academy of Anti-Aging Medicine, and the author of Harmonious Healing Blueprint: Biohacking, Regeneration & Health Resilience.
What's Discussed:
(00:00) Why skin functions as a detox organ
(07:03) How topical treatments and medications quietly increase the body’s detox burden
(11:34) Sweating, hydration, and lymphatic movement as primary detox pathways
(19:32) GLP-1s, nutrient absorption, and the real mechanism behind “Ozempic face”
(26:09) Bone density, muscle loss, and why structural facial aging is hard to reverse
(54:48) What ages skin faster than sun exposure and why sugar-driven inflammation matters

Find more from Young Goose:
Find our Elastin Protocol here: https://younggoose.com/pages/elastin-action-protocol-landing
Find our Winter Protocol here: https://younggoose.com/pages/winter-protocol
VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery: https://younggoose.com/products/vampire-exosomes
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at younggoose.com
Instagram: @young_goose_skincare

Find more from Marina Moiseyeva:
Website: https://liveharmoniouslife.com
Instagram: @liveharmoniouslife

Books' Amazon page links here:
Hardcover: https://a.co/d/asQyFGW
Paperback: https://a.co/d/gRQhEWE

Advanced skin treatments often underperform for a reason rarely addressed: regeneration cannot occur in a chronically stressed or under-resourced system. Elevated cortisol, inflammation, and metabolic imbalance weaken collagen signaling and tissue repair before any device, injectable, or modality has a chance to work.
In this episode of the Biohacking Beauty Podcast, we sit down with Joe Radich from R3 Health to unpack why physiological preparation determines treatment outcomes.
We explore how internal factors like stress, hormones, micronutrients, and metabolic health shape skin regeneration, and why modalities like peptides, hyperbaric oxygen, and exosomes only work as well as the system they’re introduced into.
Joe Radich is an NCCPA board-certified Physician Assistant specializing in regenerative medicine and the founder of R3 Health. He trains physicians and mid-level practitioners in stem cells, PRP, exosomes, and biohacking-based clinical protocols, with expertise spanning orthopedic, aesthetic, hair restoration, and regenerative applications.
What's Discussed:
(06:42) Why chronic stress and cortisol are silent drivers of visible skin aging
(10:18) Preparing the body before skin treatments and why physiology determines outcomes
(14:07) Why microneedling success depends on internal biology, not just technique
(18:55) The most common lab patterns behind poor skin regeneration and chronic inflammation
(24:31) Hormonal imbalance vs hormone deficiency and how both affect skin aging
(33:41) GHK-Cu and peptides as signaling tools for connective tissue regeneration
(38:09) Hyperbaric oxygen as a force multiplier for skin repair, recovery, and longevity
(44:06) Exosomes and regenerative biologics and why sourcing and quality determine results
Find more from Young Goose:
VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery → Vampire Exosomes
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com
Instagram: @young_goose_skincare
Winter Skincare Protocol: https://www.younggoose.com/pages/winter-protocol

Find more from Joe Radich (R3 Health):
Website: https://josephradich.com, https://r3health.co
Instagram: @joeradich_