The Journal.

For years, Moderna was a one-hit wonder, a company that bet everything on mRNA, struck gold with a COVID vaccine and then watched its stock crater as the pandemic faded. Now, the company may have found a way to fight skin cancer. An experimental mRNA-based vaccine succeeded in preventing melanoma from returning in high-risk patients, sending drug industry stocks soaring. WSJ’s Xavier Martinez traces Moderna’s wild ride from scrappy startup to the frontier of can treatment. Ryan Knutson hosts.

Further Listening:

- The FDA Commissioner on Vaccines and Public Trust

- The Creator of the Record-Setting Covid Vaccine

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Yesterday, Meta reached a settlement in a landmark social media lawsuit. The tech giant struck a deal with 48 states to pay $18 billion and make changes to the way teens can use Facebook and Instagram. WSJ’s Meghan Bobrowsky explains what this decision means for the future of social media. And Jessica Mendoza speaks with one of the settlement’s key negotiators.

Further Listening:

- The New Legal Strategy That Beat Social Media

- The Facebook Files, Part 1: The Whitelist

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The U.S. and Canada are once again embroiled in a fight over tariffs. During negotiations last week, President Trump threatened big hikes. Canada retaliated with their own tariffs. WSJ’s Gavin Bade explains how trade negotiations between two countries broke down and what could come next. Ryan Knutson hosts.

Further Listening:

- Tariffs Are Back. What’s Changed?

- Canada’s New Leader Is Ready To Take on Trump

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Yesterday, the Trump administration announced a new strategy in the war against Iran that targets the regime’s remaining economic lifelines. Treasury Secretary Scott Bessent called it an “economic D-Day.” WSJ’s Brian Schwartz explains the U.S.’s new sanctions approach and analyzes what impact it could have on the Iranian economy. Jessica Mendoza hosts.

Further Listening:

- Do Sanctions Still Work?

- Inside Trump and Netanyahu’s Complicated Relationship

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Customers of the meal kit company Blue Apron have been complaining about canceled orders, missing ingredients and incomplete recipes. The company even acknowledged in a social media post that "recent orders have fallen short." What's behind this mess? WSJ's Sarah Nassauer breaks down the chaos at Blue Apron. Imani Moise hosts.

Further Listening:

- Jersey Mike's Journey From the Shore to Wall Street

- What's Going On With Lettuce?

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