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• The Ethics Of Animal Testing

  What would you sacrifice to push efforts forward on eliminating diseases? What about to make sure our products and medicines are safe, especially for our most vulnerable?These questions lead us to ethical quagmire and, oftentimes, to the use of animals for research, testing, and experimentation. We’ve long heard the term “lab rat.” Its popularity in conversation belies an understanding that these creatures are popular subjects for experimentation. But they’re far from the only ones.Around 40,000 dogs were used as test subjects in labs last year, according to a leading advocacy group. The most common breed used are beagles.Journalist Melanie Kaplan adopted Hammie in 2013, a lab beagle who had been used for research for nearly four years. It led her down a years-long rabbit hole to find out more about her companion’s past. It took her to a sanctuary farm for former research animals in Wyoming, a naked mole rat lab at Boston University, and the homes of former researchers.We discuss her book, “Lab Dog: A Beagle and His Human Investigate the Surprising World of Animal Research.” Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

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• The CDC, RFK Jr., And Childhood Vaccine Schedules

  On Friday, the Centers for Disease Control and Prevention’s vaccine advisory panel voted to end a recommendation that all newborns be immunized at birth against hepatitis B. That guidance had been in place for more than 30 years. Hepatitis B is a highly infectious virus that can cause severe liver damage, including cirrhosis and cancer.The members of this panel, known as ACIP, were handpicked by Health and Human Services Secretary Robert F Kennedy Junior. That’s after he abruptly fired all the previous 17 members of the panel earlier this year. That which led top officials at the CDC to resign in protest.His new members have publicly stated they want to revisit the entire childhood vaccine schedule. And after the panel’s recent meeting, President Donald Trump expressed support for such a review.How will ending the recommended Hepatitis B shot for newborns affect public health? And what’s next for childhood vaccinations?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

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• 'If You Can Keep It': Trump And Matters Of Military Law

  As of Thursday, the Pentagon says it’s attacked 23 boats and killed at least 87 people as part of the Trump administration’s campaign against drug trafficking in the Caribbean.In the months since the first strike on Sept. 2, one question has emerged that Defense Secretary Pete Hegseth cannot seem to shake: Are these boat strikes legal?The White House says yes. But several members of Congress, legal experts, and former defense and intelligence officials have their doubts. Questions also remain about whether it’s legal for President Donald Trump to deploy the National Guard in cities across the country.In this installment of our weekly politics series, “If You Can Keep It,” we convene a panel of experts on military law to help us find answers.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

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• The News Roundup For December 5, 2025

  Defense Secretary Pete Hegseth was under the spotlight this week. Lawmakers on Capitol Hill are demanding video and audio of a “double-tap” strike he ordered on a boat allegedly carrying drugs into the U.S.The Trump administration has halted immigration applications from 19 countries. This comes after the shooting of two National Guard members by an Afghan national in Washington D.C.The city of San Francisco filed a lawsuit against food manufacturers over ultra processed products. It’s the first of its kind and argues that cities and states have been burdened with treating the diseases the food causes.Meanwhile, graphic depictions of at least two survivors being killed by a second U.S. military strike on an alleged Venezuelan drug boat sparked outrage on Capitol Hill. This comes as tensions between Caracas and Washington reach a fever pitch.Venezuelan President Nicolas Maduro confirmed that he did speak with President Donald Trump in a phone call that he described as “cordial.”An American delegation attended talks in Moscow, hoping to end the war in Ukraine. Russian President Vladimir Putin declined to compromise during negotiations.And the Israeli government announces it will reopen the Rafah border crossing, but only to for Palestinians to leave Gaza.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

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• Combating The Rise In Pedestrian Deaths In The US

  Between 2010 and 2022, pedestrian deaths in the U.S. jumped nearly 80 percent.Since then, the number of walkers struck and killed by cars has remained stubbornly high – with pedestrian deaths in some cities continuing to rise.What’s made our streets so dangerous and what can we do about it?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

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