Core Memory

The theme for this week’s episode is tick, tick, boom.
America is running out of time to catch up with China on manufacturing, and we’re physically incapable of spending an hour together without bringing it up. Release the glorious machines please!! We also go behind the scenes on Kylie’s reporting on motors and actuators — the unglamorous parts that sit in every joint of a humanoid robot, account for roughly 60% of what that robot costs to build, and come almost entirely from China. Her piece profiles the two startups trying to change that. Plus a new proposed bill out of Congress that would kick Unitree’s robot doggies to the curb.
Then the rockets send Ashlee off on his space tangents. Jeff Bezos’ Blue Origin had an expensive mishap recently when an explosion took out the rocket, its launch pad, and possibly America’s dreams of beating China back to the moon. Ashlee walks through why a pad explosion can be a near-death moment for a rocket company, and why SpaceX — now flying roughly every two days while everyone else is grounded or behind — increasingly just wins by default. Plus the new Starfall capsule, SpaceX’s move into making medicine and maybe chips in orbit, and the wild logic behind a $1.77 trillion IPO.
We also got into the media drama consuming our X timeline: the firing of Scott Pelley from 60 Minutes. Ashlee tweeted an opinion, the trolls came for him hard, and he pleads his case here. We’re a little biased since, well, we’re off building this whole new-media thing ourselves. Will there still be a ticking clock and a man in a suit raking in views twenty years from now? Tune in for what we think, and leave your hot take in the comments.
The Core Memory podcast is on all major platforms and on our YouTube channel over here. If you like the show, please leave a review and tell your friends.
(Ed. Kylie - Don’t think I forgot to make you a playlist. “Lazy Eye” and “New Slang” were key to my college experience. I first crushed on Rivers Cuomo thanks to “Perfect Situation.” Listen to it here, and don’t forget to leave a comment to win tickets to their tour).
OUR SPONSORS
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Do you make stuff? Do you need metal parts fast and believe in truth and justice? Then head on over to SendCutSend where you’ll get a 15 percent discount thanks to Core Memory on whatever you’re trying to build. We believe in you.
Brex
The Core Memory podcast is also sponsored by Brex, the intelligent finance platform built to help companies spend smarter and move faster.
Did we go to Texas, find a telescope ranch and then obtain an entire nebula in Brex’s honor? Oh yes, we did.
We run on Brex and so should you. Learn more about Brex right here.
Timestamps
* 00:00:00 – Intro
* 00:02:05 – The American Actuator Crisis
* 00:06:51 – WestMag vs. Atlas Motion Systems
* 00:14:21 – Uncle Sam Pays Attention
* 00:16:47 – Chinese Robot Ban
* 00:21:16 – A Robot in Every Home
* 00:24:29 – Are You AGI-pilled Yet?
* 00:27:23 – Shoutout to Micayla Sortland
* 00:31:01 – Blue Origin’s Explosive Launch
* 00:42:52 – Low Earth Orbit Drugs
* 00:49:42 – The Two-Trillion-Dollar Elon Bet
* 00:57:07 – Founders Fund’s Viral “Mafia” Game Night
* 01:01:23 – Ashlee Braves His Notifications
* 01:06:12 – Legacy Media vs. The World


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A couple of months ago, we went out to Nevada to hang with JB Straubel, the founder and CEO of Redwood Materials and the co-founder of Tesla. JB took us on a tour of Redwood’s massive battery recycling operations and showed us the company’s next chapter, which centers on building battery and solar farms to power AI data centers.
The result of our time wi…

Jacob Kimmel returns to the show. And he might have cured the hangover and liver disease. NBD.
Kimmel is the co-founder and president of NewLimit and one of the deepest thinkers in the longevity field. His company has been working to reverse the aging process in the body and has seen some stunning results with a new therapy that undoes liver damage in mice. We’re talking old mice that shrug off the effects of too much booze as if they were teenagers and that exhibit recoveries from long-term alcohol abuse.
The results have been good enough to help NewLimit raise another $435 million from the likes of Founders Fund and Thrive Capital. They’re also good enough to have NewLimit kick off a human trial of the therapy next year. And I’ll drink to that.
We discuss all of this on the podcast and then go much deeper on the longevity field, bio-tech and the collision of AI and biology.
The Core Memory podcast is on all major platforms and on our YouTube channel over here. If you like the show, please leave a review and tell your friends.
OUR SPONSORS
SendCutSend
Do you make stuff? Do you need metal parts fast and believe in truth and justice? Then head on over to SendCutSend where you’ll get a 15 percent discount thanks to Core Memory on whatever you’re trying to build. We believe in you.
Brex
The Core Memory podcast is also sponsored by Brex, the intelligent finance platform built to help companies spend smarter and move faster.
Did we go to Texas, find a telescope ranch and then obtain an entire nebula in Brex’s honor? Oh yes, we did.
We run on Brex and so should you. Learn more about Brex right here.
Timestamps
0:0) Intro3:50 What Is Epigenetic Reprogramming?7:16 Growing a Whole Animal From One Old Cell13:06 Meet Ambrosia, the AI Hunting for Youth22:44 $435 Million and the Race to Human Trials29:26 The Drunk Mice That Skip the Hangover36:48 Inside the First Human Trial43:14 Will There Ever Be a Hangover Pen?49:39 Beyond the Liver: The Delivery Problem1:03:27 Answering the Skeptics1:12:42 Will OpenAI Become a Drug Company?1:23:53 The Health Story Bigger Than AI?1:35:00 How Far Behind Is the US vs China?1:53:10 Can We Build Computers From Neurons?



This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe

Our guest this week is the renowned science fiction author Hannu Rajaniemi. And he has come to terrify and then perhaps comfort you.
Rajaniemi made an immediate name for himself in literary circles with his debut novel The Quantum Thief. He’s since written a string of novels that explore the directions technology might take in the future, and his work always stands out for its creativity and imagination.
These days, Rajaniemi is putting those skills to very practical use at Red Queen Bio. The company appeared near the end of last year with a focus on AI biosecurity. Red Queen’s main objective is to try and outthink and outflank bad actors and/or AI systems run amok that might unleash bioweapons onto the world. As such, Red Queen must concoct all sorts of dark scenarios and then come up with ways to undercut and defeat them.
Rajaniemi has a background in mathematics, physics and bio-tech and possesses one of those fast-twitch minds that makes the rest of us envious. We talked about his life and career and, obviously, the wild reality we now inhabit.
The Core Memory podcast is on all major platforms and on our YouTube channel over here. If you like the show, please leave a review and tell your friends.
OUR SPONSORS
SendCutSend
Do you make stuff? Do you need metal parts fast and believe in truth and justice? Then head on over to SendCutSend where you’ll get a 15 percent discount thanks to Core Memory on whatever you’re trying to build. We believe in you.
Brex
The Core Memory podcast is also sponsored by Brex, the intelligent finance platform built to help companies spend smarter and move faster.
Did we go to Texas, find a telescope ranch and then obtain an entire nebula in Brex’s honor? Oh yes, we did.
We run on Brex and so should you. Learn more about Brex right here.



This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe

We are back with another episode of Ashlee and Kylie gossiping about the latest in Silicon Valley.
First, a re-cap of our Alexandr Wang interview — his first real sit-down in eleven months — and what it actually revealed about Meta’s AI play. Wang seemed nervous hashing out the strategy in the studio, and we both keep circling the same puzzle: Meta has endless compute and top talent in Nat Friedman and Daniel Gross, so why does the model still feel underwhelming?
We get into Eric Schmidt getting booed off a commencement stage at the University of Arizona, which becomes a longer conversation about the generational fury aimed at AI. Everyone Kylie’s age seems to hate it, but is it due to misinformation or legitimate anger about jobs and data centers? Ashlee admits he’s more confused by this moment than anything he’s covered in tech: the predicted Wall Street collapse hasn’t come, the models keep getting better, and the valuations still make no sense.
Then, the news that broke minutes before we hit record: OpenAI won the Musk lawsuit on statute-of-limitations grounds. We dig into whether OpenAI’s shift from open-source nonprofit to for-profit was an original sin or just the only way to pay for the compute. Also, Ashlee’s texts with Sam Altman being part of discovery?!
In more Musk news, Bloomberg reported that Musk’s xAI stiffed staff on the $420 they were promised for feeding their tax returns into Grok. One host would decidedly not trust a chatbot with their financials, and the other already has. We also get into the strange new bedfellows: SpaceX selling compute to Anthropic, a company Musk has long been philosophically against.
We even take you behind the scenes at Core Memory — so study up and watch our latest videos on Phantom Neuro and Starfront Observatories. Consider this your homework on mind-controlled arms and galaxy photography. Essay due on our desk by morning.
Don’t forget you could win tickets to the Weezer tour by leaving an amazing review for our podcast wherever you listen.
The Core Memory podcast is on all major platforms and on our YouTube channel over here. If you like the show, please leave a review and tell your friends.
OUR SPONSORS
SendCutSend
Do you make stuff? Do you need metal parts fast and believe in truth and justice? Then head on over to SendCutSend where you’ll get a 15 percent discount thanks to Core Memory on whatever you’re trying to build. We believe in you.
Brex
The Core Memory podcast is also sponsored by Brex, the intelligent finance platform built to help companies spend smarter and move faster.
Did we go to Texas, find a telescope ranch and then obtain an entire nebula in Brex’s honor? Oh yes, we did.
We run on Brex and so should you. Learn more about Brex right here.


This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe